Brian Mitchell is a former NFL running back and return specialist. He played college football at University of Southwestern Louisiana where he was a quarterback.

Mitchell is considered one of the greatest return specialists in NFL history. He was originally drafted by the Washington Redskins in the fifth round (130th overall) of the 1990 NFL Draft. Mitchell also played for the Philadelphia Eagles and the New York Giants. He is currently (2021) second on the NFL's all-time list in all-purpose yardage with 23,330 yards, behind Jerry Rice. He is also first all-time for combined yardage for a non-wide receiver, also as of 2021. His 13 special teams touchdowns are second in NFL history, behind Devin Hester, and his nine punt return touchdowns are third behind Eric Metcalf with 10, and Hester with 14 (all records hold as of 2021). Mitchell was ranked the second greatest specialist in NFL history by NFL Network's NFL Top 10 Return Aces.

Since retiring, Mitchell has been a TV and radio host and analyst for a variety of outlets. On TV, he is currently the NFL analyst for WUSA-TV in Washington D.C., where he co-hosts the station's Sunday night wrap-up program entitled "Sports Plus. On September 14, 2016 Brian Mitchell was nominated for the 2017 class of the Pro Football Hall of Fame.